Screening for ?-glucosidase inhibitors from marine invertebrates extracts
- VernacularTitle:海洋无脊椎动物中?-葡萄糖苷酶抑制剂的初步研究
- Author:
Lixin ZHANG
;
Feng XUE
;
Ruiying GAI
- Publication Type:Journal Article
- Keywords:
marine invertebrates;
?-glucosidase inhibitors;
screening
- From:
Chinese Journal of Marine Drugs
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To screen for ?-glucosidase inhibitors from the extracts of marine invertebrates collected at the seashore of Qingdao China.Method The 95% ethanol extracts of 33 species of marine invertebrates were screened for the presence of ?-glucosidase inhibitors using rapid colorimetric method.Result Some extracts have inhibitory activity against ?-glucosidase,among which the extracts of Tubularia marina,Asterina pectinifera,Apostichopus japonicus and Scapharca subcrenata have much higher inhibitory rate: 56.1%,67.3%,62.2%,and 66.3% at the concentration of 0.6 mg?mL-1.Conclusion The results suggested that marine invertebrates are sources of new ?-glucosidase inhibitors.
