PTEN expression in breast cancer and its correlation with the tumor angiogenesis
- VernacularTitle:基因PTEN表达与乳腺癌肿瘤血管生成的关系
- Author:
Jian LIU
;
Pengyuan XU
- Publication Type:Journal Article
- Keywords:
Breast neoplasm;
PTEN protein;
Angiogenesis
- From:
Journal of Medical Postgraduates
2003;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the expression of PTEN(phosphatase and tensin hmmlogy deleted on ten) in the breast cancer and the relationship with the tumor angiogenesis.Methods:The expression of PTEN and MVD were detected by immunohistochemical SP method in paraffin section from 53 women with primary breast cancer and 10 subjects of hyperplasia of mammary glands.Results:The higher lever PTEN expression in 53 case with the rate 49.1 %(26/53),which was reduced compared with the expression in benign hyperplasia of mammary glands(P
