Alternariol enhanced DNA polymerase ? expression in NIH3T3 cells
- VernacularTitle:互隔交链孢酚增加NIH3T3细胞中DNA聚合酶?表达
- Author:
Jimin ZHAO
;
Ge JIN
;
Pei LI
;
Mingyao ZHAO
;
Hongyan YANG
;
Zhimin ZHENG
;
Ziming DONG
- Publication Type:Journal Article
- Keywords:
DNA POL?;
alternariol;
NIH3T3 cells
- From:
Basic & Clinical Medicine
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of Alternariol(AOH) on DNA polymerase ?(DNA POL?)expression in NIH3T3 cells.Methods RT-PCR,Immunocytochemistry and Western blot were used to detected mRNA and the protein levels of DNA POL? in NIH3T3 cell line induced by AOH.Results The expression of DNA POL? in NIH3T3 cells contaminated by AOH was significantly higher than that in the control group(P
