Expression of caveolin-1 in tumor and its clinical significance
- VernacularTitle:Caveolin-1在肿瘤中的表达及临床意义
- Author:
Weijia DONG
;
Jianguo ZHANG
;
Jingwu YANG
;
Bo ZHANG
- Publication Type:Journal Article
- Keywords:
caveolae;
caveolin-1;
tumor
- From:
Basic & Clinical Medicine
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Caveolin-1(Cav-1) is a scaffold protein of caveolae that acts as a tumor modulator by interacting with cell adhesion molecules and signaling receptors.Evidence from a variety of studies indicate that caveolin-1 exhibits the heterogeneity of Cav-1 expression in different tumors.Current research has clearly established a role for Cav-1 as a a novel prognostic marker,Future studies will undoubtedly offer novel exciting opportunities to develop anti-cancer therapies.
