Changes in oxygen partial pressure in rabbit ear scar tissues during the mature process
- VernacularTitle:兔耳瘢痕成熟过程中组织内氧分压的变化
- Author:
Jun TAN
;
Gang ZHANG
;
Gaofeng LI
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2007;0(42):-
- CountryChina
- Language:Chinese
-
Abstract:
Mature animal models of rabbit ear scars were made from formation to maturation. Tissue oxygen partial pressure was determined by percutaneous oxygen monitoring at 14,30,60 and 90 days,and then pathology examination was performed. Fourteen days after surgery,bright red granulation tissues had a large number of inflammatory cells and angiogenesis; oxygen partial pressure was (0.81?0.25) kPa. Thirty days after surgery,the scars were significantly higher than the normal skin,bright red,made up of a large number of fibroblasts and capillary in the organizations; the partial pressure of oxygen was (1.98? 0.26) kPa. At 60 days after surgery,the scars were shrinking; color was light; the organization fibroblast cells and microvessel decreased; partial pressure oxygen was (1.86?0.60) kPa. Ninety days after surgery,the scars were flat; color was white; organizational structure was closed to normal skin; oxygen partial pressure was (13.70?1.16) kPa (P
