Study on the immune function in local mucosa post newcastile disease vaccination of chicken infected with chicken anemia virus

Publication Type:Journal Article
From: Chinese Journal of Pathophysiology 2001;17(8):778-
CountryChina
Language:Chinese
Abstract: Chickens were infected with CAV at one-day-old and 8 days later, the infected and uninfected chickens were vaccinated with La Sota vaccine. At 7\, 14\, 28 days post vaccination, the number of T cells and IgG, IgM and IgA antibody producing cells in Harderian gland and cecal tonsil, the content of IgG, IgM and IgA in tear, trachea fluid, intestinal fluid and bile as well as the hemoagglutination inhibition (HI) titer in tear and bile were detected. The results showed that the number of T cells and IgG, IgM and IgA antibody producing cells in Harderian gland and cecal consil, the content of IgG, IgM and IgA in tear, trachea fluid, intestinal fluid and bile as well as the HI titer in tear and bile post ND vaccination of CAV infected chickens were decreased significantly than those of uninfected vaccinated chickens. These indicated that the immune response function was markedly weakened in local mucosa of digestive and respiratory tract post ND vaccination of CAV-infected chickens.