Functions of The 3′ Untranslated Region of Eukaryotic mRNA
- VernacularTitle:真核生物mRNA 3′非翻译区的功能
- Author:
Haizhen WANG
;
Ying WANG
;
Dinggan LIU
- Publication Type:Journal Article
- Keywords:
mRNA, 3′untranslated region, function
- From:
Progress in Biochemistry and Biophysics
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Functions of the 3′untranslated regions (3′UTR) of eukaryotic mRNAs are complicated. They can control the stability and intracellular localization of mRNAs, and direct the translation of special amino acids. Mutations in the 3′UTR of some mRNA can cause serious diseases, and recent studies showed that the 3′UTR of some eukaryotic mRNAs possess tumor-suppression function.