Drug Resistant Genes of CARB and aac(6′)-Ⅱ Prevailing in Pseudomonas aeruginosa Isolated from Burned Patients
- VernacularTitle:CARB、aac(6′)-Ⅱ基因在铜绿假单胞菌烧伤患者分离株中流行
- Author:
Yuhong PAN
;
Feng ZHANG
;
Xuan HUANG
;
Huali CHENG
;
Ling QIN
;
Zuhuang MI
- Publication Type:Journal Article
- Keywords:
Pseudomonas aeruginosa;
?-Lactamases;
Aminoglycosides;
Drug resistant gene
- From:
Chinese Journal of Nosocomiology
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate drug resistant genes associated with beta-lactamases,aminoglycosides and sulfonamides in Pseudomonas aeruginosa isolated from burned patients.METHODS Common drug resistant genes associated with beta-lactamases,aminoglycosides and sulfonamides of 20 strains of P.aeruginosa isolated from burned patients were detected by PCR.RESULTS The positive rates of genes of TEM,aac(6′)-Ⅰb,sul1 and ant(3″)-Ⅰwere 85%,85%,90% and 10%,respectively and genes of CARB and aac(6′)-Ⅱ were both positive(100%).Genes of oprD2 were all absent and genes of SHV,GES,IMP,VIM,DHA and armA were all negative.Furthermore,drug resistant genes of strains isolated from different sites of one patient on different time could be different.CONCLUSIONS Drug resistant genes of CARB and aac(6′)-Ⅱprevail in P.aeruginosa isolated from burned patients.Detections of drug resistant genes in P.aeruginosa isolated,especially continuously isolated from burned patients are essential.
