Role of retrograde messenger NO in long-term potentiation
- VernacularTitle:逆行信使NO在突触长时程增强过程中的作用
- Author:
Wei LU
;
Ruibin SU
;
Jin LI
- Publication Type:Journal Article
- Keywords:
retrograde messenger;
NO;
LTP;
signal transduction
- From:
Basic & Clinical Medicine
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
As an important messenger molecule, NO exists in both peripheral and central nervous system (CNS). Recently, NO was proved to play a critical role in CNS, especially in synaptic plasticity. As a kind of retrograde messenger, it plays some roles in the induction and maintenance of LTP through activation of downstream pathway or molecules, such as NO-cGMP-PKG, ADPRT and C-FOS.
