Influence of the number of balloon inflations during primary percutanoeus coronary intervention on myocardial perfusion and the extent of myocardial necrosis in patients with ST-segment elevation myocardial infarction
- VernacularTitle:直接经皮冠状动脉介入术中球囊充盈次数对心肌灌注和心肌坏死程度的影响
- Author:
Guisong WANG
;
Wei ZHAO
;
Lijun GUO
- Publication Type:Journal Article
- Keywords:
Myocardial infarction;
Angioplasty,transluminal,percutaneous coronary;
Myocardial reperfusion;
Ischemic postconditioning
- From:
Chinese Journal of Interventional Cardiology
1996;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship of the number of balloon inflations during primary percutanoeus coronary intervention(PCI) with myocardial perfusion and the extent of myocardial necrosis,and to identify the potential clinical efficacy of ischemic postcondioning in patients undergoing Primary PCI.Methods One hundred and fourty patients with ST-segment elevation myocardial infarction(STEMI) who underwent primary PCI were eligibly enrolled for retrospective analysis.The infarct-related artery(IRA) in all patients had to be either left anterior descending artery(LAD) or right coronary artery(RCA) with TIMI 0 flow grade and no collateral filling prior to intervention,and had to be completely reperfused with TIMI Ⅲ flow grade after PCI.Patients with cardiac arrest,cardiogenic shock,previous MI and pre-infarct angina were excluded.Patients were divided into two groups for analysis based on the number of balloon inflations performed during primary PCI:Group A included all patients in whom 1-2 inflations were applied,while patients in Group B received 3 or more inflations.Myocardial perfusion was evaluated by myocardial blush grade and ST-segment resolution.The extent of myocardial necrosis was evaluated by peak values of CK and CK-MB release and predischarge left ventricular ejection fraction(LVEF) measured by echocardiogram.Results The 2 groups showed similar baseline characteristics,while patients in Group B received more balloon inflations than those in Group A(4.7?0.9 vs.1.8?0.2,P0.05),but decreased to 1.65?0.49 mm and 0.98?0.37 mm(P
