Inflammation-targeted MR molecular imaging in atherosclerosis disease
- VernacularTitle:动脉粥样硬化炎症靶向的MR分子影像学
- Author:
Rui ZHAO
;
Gang DENG
- Publication Type:Journal Article
- Keywords:
Molecular imaging;
Atherosclerosis;
Magnetic resonance imaging;
Inflammation
- From:
Journal of Medical Postgraduates
2003;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Atherosclerosis,as a chronic inflammatory vascular disease,involves many cellular and molecular events in its formation and progression from an early fatty streak lesion to a highly dangerous rupture-prone plaque.The vulnerability or destabilization of atherosclerotic plaques is closely associated with plaque composition.Such imaging modality as magnetic resonance imaging(MRI),which allows of the evaluation of the plaque composition at the cellular and molecular level,may differentiate vulnerable and destabilized plaques and monitor the efficacy of antiatherosclerotic therapies.This paper gives an overview of molecular imaging strategies currently used for targeting the inflammation markers of atherosclerotic plaque vulnerability.
