Detection and Assay of Beta-lactamase and Drug Resistance of Stenotrophomonas maltophilia
- VernacularTitle:嗜麦芽寡养单胞菌?-内酰胺酶检测及耐药性分析
- Author:
Jun SHE
;
Caihua SHAN
- Publication Type:Journal Article
- Keywords:
Stenotrophomonas maltophilia;
Extended-spectrum beta-lactamases;
Metallo ?-lactamase;
Resistance
- From:
Chinese Journal of Nosocomiology
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To study the drug resistance of Stenotrophomonas maltophilia in order to direct clinical drug application.METHODS The S.maltophilia was identified and its sensitivity was analyzed with VITEK2-AMS.The extended-spectrum beta-lactamases(ESBLs) and metallo ?-lactamase(MBL) were screened by double-disk synergy test and double-disk confirmatory test.RESULTS The resistance rate of S.maltophilia to cefoperazone-sulbactam,levofloxacin and SMZ-TMP was the lowest,accounted for 12.50%,13.64% and 14.77%,respectively.The ESBLs positive rate was 69.32%,the MBL positive rate was 69.32%.CONCLUSIONS The multidrug resistance of S.maltophilia is serious and full dose use of two or more antibacterials is recommended.
