Distribution and Drug Resistance Analysis of Pathogens in Hematology Department Ward
- VernacularTitle:血液病房感染病原菌分布及耐药性分析
- Author:
Chunyan LI
- Publication Type:Journal Article
- Keywords:
Hematology department ward;
Bacterial pathogen;
Drug resistance
- From:
Chinese Journal of Nosocomiology
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the clinical distribution characteristics and drug resistance of pathogens in hematology department ward during recent two years,and instruct clinical application of antibiotics reasonably.METHODS The bacteria were identified by VITEK-60 with GNI+,GPI and YBC.Drug sensitivity tests of bacteria were performed by K-B method.The results were analyzed by WHONET 5.3 software.RESULTS The results showed that 370 strains of pathogens were isolated from all detected samples.The composition ratio of Gram-positive bacteria,Gram-negative bacteria and fungi was 59.7%,32.4% and 7.8%,respectively.Coagulase negative Staphylococcus,Escherichia coli,Pseudomonas aeruginosa,Klebsiella pneumoniae and Acinetobacter baumannii were the most frequently isolated pathogens.The ESBLs producing strains in E.coli and Klebsiella spp were 59.3% and 24.2%,respectively.The MRSA in S.aureus and MRCNS in coagulase negative Staphylococcus were 18.2% and 87.8%,respectively.CONCLUSIONS Inspecting pathogens and studying the trend of their drug resistance are important to rationally select antibiotics,reduce infection incidence and mortality rate,and decrease the occurrence of drug resistant strains.
