Relationship Between Resistance of Enterobacter cloacae and Consumption of Antibiotics
- VernacularTitle:阴沟肠杆菌的耐药性与抗菌药物使用量的相关性分析
- Author:
Baoxiang PEI
;
Qibei WU
;
Xiue GUO
- Publication Type:Journal Article
- Keywords:
Enterobacter cloacae;
Drug resistance;
Antibiotics
- From:
Chinese Journal of Nosocomiology
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the quantity of antibiotics prescribed yearly from 2001 to 2006 and the resistance of Enterobacter cloacae,and analyze the correlation between them.METHODS Its susceptibility to antimicrobial agents was performed by disk diffusion method and analyzed by WHONET 5.3.The correlation between DDDs and the resistance was analyzed using statistics.RESULTS The percentage of resistance of E.cloacae to the five drugs was decreased during recent six years.The most of decreased tendency was amikacin,its resistance in 2006 decreased 28% than that in 2001.The consumption of five drugs all decreased.The consumption of ceftazidime in 2006 was 1/12 compared in the 2004.The consumption of ciprofloxacin in 2006 was 1/8 compared in 2001.The analysis revealed a significant positive correlation between the resistance and DDDs of amikacin(r=0.8826,P
