Adnexal mass in Pregnancy: Correlation of Sonographic Findings and Pathology.
- Author:
Jung Ae MIN
1
;
Suk Joo CHOI
;
Kyung Lan JUNG
;
Soo Young OH
;
Jong Hwa KIM
;
Cheong Rae ROH
Author Information
1. Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. crroh@smc.samsung.co.kr
- Publication Type:Original Article
- Keywords:
Adnexal mass;
Pregnancy;
Ultrasonographic finding;
Tumor marker
- MeSH:
Female;
Humans;
Laparotomy;
Medical Records;
Pathology*;
Pregnancy Outcome;
Pregnancy*;
Retrospective Studies;
Teratoma;
Biomarkers, Tumor;
Ultrasonography*
- From:Korean Journal of Perinatology
2007;18(4):345-351
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE:The purpose of this study was to investigate the role of sonographic findings and tumor markers in predicting malignancy of adnexal masses in pregnancy. METHODS:From January 1995 to September 2005, 190 cases of adnexal masses were operated during pregnancy. We reviewed their sonographic findings and medical records retrospectively. Sonographic features and tumor markers were correlated with malignant pathology. Pregnancy and neonatal outcomes were also studied after treatment of adnexal mass during pregnancy. RESULTS:From 190 cases, there were 10 cases (5.3%) of malignant tumor or tumors of borderline malignancy. In the 180 cases of benign adnexal mass, the most common type was mature cystic teratoma (36.7%). Preoperative sonographic findings were available in 110 cases. The median size was 6.3 cm for benign masses and 7.7 cm for malignant masses (p=0.05). Mixed echogenecity, septa and mural nodule were more frequently found in malignant masses (p=0.003, 0.029, 0.013, respectively). Tumor markers were available in 47 cases. In the 1st trimester, the level of serum CA-125 of the patients with benign masses were not different from those with malignant masses. However, in the 2nd and 3rd trimester, the difference was statistically significant (p=0.031). Forty- six patients underwent antepartum surgery and the overall pregnancy outcome was similar between the laparoscopic group and the laparotomy group. CONCLUSION:Mixed echogenecity, septa and mural nodule showed significant correlation with malignant adnexal mass in pregnancy.
