Obstetrical Outcomes of Idiopathic Thrombocytopenic Purpura in Pregnancy.
- Author:
Song Ah SONG
1
;
Seung Ju SHIN
;
Young Il CHOI
;
Su Hyen KIM
;
Ji Eun SHIN
;
Yei Eun OH
Author Information
1. Department of Obstetrical and Gynecology, College of Medicine, Pochon CHA University, Soeul, Korea. sjshin@cham.ac.kr
- Publication Type:Original Article
- Keywords:
ITP;
pregnancy;
delivery;
platelet
- MeSH:
Blood Platelets;
Cesarean Section;
Diagnosis;
Female;
Hemorrhage;
Humans;
Immunization, Passive;
Infant;
Infant, Newborn;
Mothers;
Parturition;
Platelet Count;
Platelet Transfusion;
Pregnancy*;
Pregnant Women;
Purpura, Thrombocytopenic, Idiopathic*;
Retrospective Studies
- From:Korean Journal of Perinatology
2007;18(4):378-384
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: Idiopathic thrombocytopenic purpura (ITP) frequently occurs in young women. Consequently, clinicians often give medical treatment to pregnant women who are diagnosed with ITP. This study might help to make a clinical guidelines for obstetrical ITP patients and their infants. METHODS: We retrospectively investigated the medical charts of 19 cases of deliveries and 22 neonates which from mothers with the diagnosis of ITP during pregnancy from March 1998 to March 2007. RESULT: Corticosteroid treatment was administrated in 13 cases, high-dose immunoglobulin therapy in 3 cases, and concentrated platelet transfusion in 17 cases during their antenatal care. Ten (45%) vaginal deliveries and twelve (55%) cesarean sections were performed. There were no obstetrical complications associated with their ITP and only four infants with platelet counts below the 150,000/micronLiter were reported after birth. However there were not any signs and symptoms of neonatal complications resulting from their maternal ITP. CONCLUSION : Our results demonstrate that mothers with ITP can successfully deliver healthy infants in most case. Although maternal and fetal bleeding may occur, such a fatal complication is uncommon.
