Factors influence long-term effect of diabetes mellitus treated by islet transplantation
- VernacularTitle:影响胰岛移植治疗糖尿病远期效果的因素
- Author:
Tao SONG
;
Binhong HUANG
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2007;0(31):-
- CountryChina
- Language:Chinese
-
Abstract:
Islet transplantation is an effective method treating insulin-dependent diabetes mellitus, which is apt to supersede pancreas transplantation currently. Although human islet transplantation has already performed successfully, its long-term effect is still unsatisfying. Reasons causing loss of islet function is still not fully understood to date. Thus, deep research of factors influencing transplanted islet survival is of importance to improve long-term effect of islet transplantation. Patient selection and tissue matching, collection, preservation and transport of pancreatic organ, isolation and purification of islet cells, implement of islet transplantation, blood glucose control and immunosuppressive drug application during islet transplantation period, functional assessment after islet transplantation, etc. completion quality of each of these technical links is the factor influencing islet transplantation.
