The distribution of killer immunoglobulin-like receptor genes in Qingdao Han population
- VernacularTitle:青岛地区汉族人群杀伤细胞免疫球蛋白样受体基因多态性研究
- Author:
Changying LI
;
Bin HU
;
Tongxian WANG
- Publication Type:Journal Article
- Keywords:
Immunoglobulin-like receptor(KIR);
Gene distribution;
Gene frequency
- From:
Chinese Journal of Blood Transfusion
2008;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the distribution of killer immunoglobulin-like receptor(KIR) genes in Qingdao Han population and its difference from other populations.Methods The KIR genotypes of 81 cascs were examined by PCR-SSP,and the gene frequencies were calculated and compared to those of other populations.Result Fourteen KIR genes and 2 pseudo genes were found and all had different gene frequencies.Conclusion All inhibit-gene frequencies are higher than their active-gene frequencies.KIR gene frequencies are different between the southern and northern Chinese Han people.Many of them increase gradually from the south to the north.The KIR gene distributions of Korean and Japanese populations are close to the Northern Chinese Han population.
