Detection of antibodies against the hypervariable region 1 of hepatitis C virus
- VernacularTitle:献血人群中丙型肝炎病毒第1高变区抗体检测及意义
- Author:
Bingshui XIU
;
Guohua WANG
;
Heqiu ZHANG
- Publication Type:Journal Article
- Keywords:
Hepatitis C virus;
Hypervariable region 1;
Anti-HCV antibody
- From:
Chinese Journal of Blood Transfusion
2008;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To detect antibodies against the hypervariable region 1(HVR1) of hepatitis C virus in blood screening.Methods The HVR1 antibodies were detected by F4HVR1 antigen,and then were compared with other antibodies of HCV.Results Among HCV-RNA positive samples,HVR1 antibody was 96.8% positive.The positive rate of HVR1 antibodies in 90 suspected HCV-infected samples was 61.1%,which was close to those against C and NS3,and higher than NS4 and NS5(P
