Determination of T lymphocyte subgroups in endobronchial tuberculosis patients
- VernacularTitle:支气管内膜结核患者外周血T淋巴细胞亚群检测分析
- Author:
Nanlan MA
;
Zhaoping SUN
;
Xia ZHANG
;
Huijuan MAO
- Publication Type:Journal Article
- Keywords:
Tuberculosis;
Immunological mechanism;
T lymphocyte subgroups
- From:
Journal of Medical Postgraduates
2003;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To gain an insight into the immunological mechanism of tuberculosis by observing the variation of T lymphocyte subgroups in endobronchial tuberculosis(EBTB) patients.Methods:The variation of T lymphocyte subgroups was determined by flow cytometry in 23 EBTB patients and 25 physical examinees and results were compared.Results:The value of CD8 T lymphocytes was significantly lower in the EBTB patients than in healthy controls(P0.05).Conclusion:The pathogenesis of tuberculosis is associated with the changes in the immune system.CD4 and CD8 T lymphocytes play an important role in the cell-mediated immune response.
