Clinical evaluation of dinoprostone pessary for cervical ripening and labor induction in term pregnancy
- VernacularTitle:地诺前列酮栓剂用于足月妊娠促宫颈成熟和引产的临床评价
- Author:
Jun WU
;
Qiuming ZHOU
- Publication Type:Journal Article
- Keywords:
Dinoprostone pessary;
Term pregnancy;
Cervical ripening,Labor induction
- From:
Journal of Medical Postgraduates
2003;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the efficacy and safety of controlled-release dinoprostone pessary(propess) in cervical ripening and intermediate labor induction.Methods:Eighty primiparas with uterogestation and Bishop score ≤6 points and no vaginal delivery taboo were equally divided into a study and a control group.The former received intravaginal administration of propess and the latter intravenous injection of low-dose oxytocin by the randomized control method.Comparisons were made of the Bishop score,delivery and the state of the fetuses and neonates between the two groups.The side effects of propess were observed.Results:Bishop scores were 7.75?2.227 and 6.38?2.862 in the study and the control group respectively 12 hours after the medication,significantly higher than 4.23?1.025 and 4.15?1.099 before the induction(P 0.05).The major side effect of propess was the over-frequent and over-strong contraction of the uterine,which occurred in 2 cases in the study group but subsided after its removal.Conclusion:Dinoprostone pessary,effective,safe and convenient,is obviously superior to oxytocin in cervical ripening and labor induction.
