Bisphosphonates in the treatment of cancer
- VernacularTitle:二膦酸盐用于肿瘤治疗的研究进展
- Author:
Haiyang GONG
;
Zhengdong CAI
- Publication Type:Journal Article
- Keywords:
Bisphosphonate;
Zoledronic acid;
Bone;
Cancer;
Metastasis
- From:
Journal of Medical Postgraduates
2003;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Because of their ability to inhibit osteoclast-mediated bone destruction,bisphosphonates are widely used in the treatment of malignant bone diseases.Recent preclinical evidence shows that bisphosphonates not only exert direct anti-tumor effects but also have anti-angiogenic properties.And furthermore,they may act synergistically with other chemotherapeutics or T cells on tumors.These new findings are ushering in the possible application of bisphosphonates as anti-tumor therapeutics in clinical practice.
