The expression and clinical significance of Ezrin,CD44v6 in the gastric carcinoma
- VernacularTitle:Ezrin和CD44v6在胃癌中的表达及临床意义
- Author:
Jing QI
;
Renmin ZHU
;
Hangbo ZHOU
;
Min ZHANG
- Publication Type:Journal Article
- Keywords:
Gastric carcinoma;
Ezrin;
CD44v6;
Immunohistochemistry
- From:
Journal of Medical Postgraduates
2003;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the expression of Ezrin and CD44v6 in gastric carcinoma and their correlations to clinicopathologic features. Methods:The expression of Ezrin and CD44v6 were detected by immunohistochemistry in gastric carcinoma(n=53) and normal gastric mucosa(n=20).Results:①The positive expression rates of Ezrin in gastric carcinoma and normal gastric mucosa were 56.6% and 30.0%.While the positive expression rates of CD44v6 in gastric carcinoma was 58.5% and no expression in normal gastric mucosa.②The expression of Ezrin was correlated to the differentiation(P0.05).③The expression of Ezrin was positively correlated with that of CD44v6 in gastric carcinoma(rs=0.740,P
