Mechanisms of Drug Resistance in Multidrug-resistant Strains of Acinetobacter baumannii
- VernacularTitle:多药耐药鲍氏不动杆菌对5类抗菌药物耐药机制研究
- Author:
Zuhuang MI
;
Ling QIN
- Publication Type:Journal Article
- Keywords:
Acinetobacter baumannii;
Multidrug-resistance
- From:
Chinese Journal of Nosocomiology
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate mechanisms of drug resistance in multidrug-resistant strains of Acinetobacter baumannii(MDR-ABA).METHODS The resistant genes related to 5 kinds of antibiotics were detected by using polymerase chain reaction and verified by DNA sequencing.RESULTS In 30 strains of MDR-ABA,the positive rates of TEM,ADC,armA,aac(3)-Ⅰ,ant(3″)-Ⅰ,dfrA12 and sul1 were 63.3%,70.0%,30.0%,90.0%,90.0%,53.3% and 80.0%,respectively.CONCLUSIONS There are high positive percentages of TEM,ADC,armA,aac(3)-Ⅰ,ant(3″)-Ⅰ,dfrA12 and sul1 genes in MDR-ABA.
