Mechanism and Adverse Effect of Quinolones
- VernacularTitle:喹诺酮类药物的作用机制及不良反应
- Author:
Huiping SUN
;
Lili CAI
;
Fuqin YAN
;
Xia LI
- Publication Type:Journal Article
- Keywords:
Quinolones;
Mechanism;
Adverse effect;
Drug in combination
- From:
Chinese Journal of Nosocomiology
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To understand the mechanisms,adverse effect and notices in use of quinalones.METHODS The adverse effect of quinalones used sinylely or in combination was collected and analyzed.RESULTS Serious central nerve system side-effects,phototoxicity,hepatotoxicity hemolytic anemia,uremia and so on could be found in few cases.Some quinolones could result in Q-T interval elongation inducing the severe ventricular dysrythmia.The serum glucose also could be affected when quinolones were used together with the medications for diabetes.CONCLUSIONS The key points for quinolones usage are rational use and paying attention to their safety.
