A Case of Delayed Peripheral Polyneuropathy Induced by Organophosphorus Intoxication.
- Author:
Won Young JUNG
1
;
Myung Sik LEE
;
Il Saing CHOI
;
Je Geun CHI
Author Information
1. Department of neurology, Yong Dong Severance Hospital, College of Medicine, Yonsei University.
- Publication Type:Case Report
- MeSH:
Adult;
Axons;
Diagnosis;
Extremities;
Female;
Humans;
Organophosphate Poisoning;
Phosphorylation;
Polyneuropathies*
- From:Journal of the Korean Neurological Association
1988;6(2):261-267
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Delayed peripheral polyneuropathy caused by organophosphorus intoxication is not uncommon. This is a case report of 32 years old female with peripheral polyneuropathy which is appeared two weeks after organophosphorus poisoning. It is characterized by calves pain followed by minmal sensory change and predominant motor weakness affecting the distal part of the limbs. The electrophysiologic and pathologic studies support the clinical diagnosis. The exact pathogenesis is still debated, but phosphorylation of neurotoxic esterase (NTE), followed by "aging" process was suspected to play a role in the development of axonal degeneration.
