Research progress of the molecules related to bone regeneration in bone tissue engineering
- VernacularTitle:骨组织工程中骨再生相关分子的研究进展
- Author:
Jianguo ZHAO
;
Weidong XU
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2007;0(28):-
- CountryChina
- Language:Chinese
-
Abstract:
The technology of bone tissue engineering has got rid from autologous bone implant and allograft bone. With the development in recent 20 years,the basic pattern of tissue engineered bone has already been constructed,consisting of related molecules to bone regeneration,active cells for osteogenesis and scaffold materials. The related molecule to bone regeneration is the dominant factor to determine the bio-activity of tissue engineered bone,and also is the key researches in the field of bone tissue engineering. As the molecule bio-mechanism of bone regeneration has been elucidated and molecule bio-techniques have been combined with bone tissue engineering,many achievements regarding the related molecules to bone regeneration are observed in bone induction mechanism,vector,gene therapy technology and the combined use,which all improve the effect of tissue engineered bone on repairing the bone defects.
