Prediction for Helper T Cell Epitopes and its Application in Vaccine Development against Parasite Infection
- VernacularTitle:辅助T细胞表位预测及其在抗寄生虫疫苗研发中的应用
- Author:
Donghua SHAO
;
Xingang FENG
- Publication Type:Journal Article
- Keywords:
Helper T cell;
Epitope prediction;
Vaccine;
Parasite
- From:
Chinese Journal of Parasitology and Parasitic Diseases
1987;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Cellular immunity plays an important role in defense against diseases, such as pathogenic infection,autoimmunity and tumor. With the progress of molecular immunology, mechanisms of T cellular immunity, and the T cell epitopes and functional genomics, studies on the prediction based on data-drived for T cell epitopes has been highlighted, and could be one of the useful tools for application in vaccine development. This review summarizes theory and methodology of prediction for helper T cell epitopes, and their application in vaccine development against parasites, and new research directions are also discussed.
