Effects of basic fibroblast growth factor and Gingkgo biloba extra on experimental cerebral infarction
- VernacularTitle:碱性成纤维细胞生长因子和银杏叶提取物对实验性脑梗死的作用
- Author:
Dan HE
;
Huaijun LIU
;
Shuochun WU
- Publication Type:Journal Article
- Keywords:
cerebral infarction;
basic fibroblast growth factor;
Gingkgo biloba extra
- From:
Journal of Clinical Neurology
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of basic fibroblast growth factor (bFGF) and Gingkgo biloba extra(GbE) on experimental cerebral infarction. Methods 40 healthy adult cats were equally devided into group A with sodiumchloride, group B with bFGF, group C with GbE and group D with bFGF+GbE in random.All animals were operated to establish the feline models of cerebral focal ischemia-reperfusion by the approach of left transorbital. The certain madicine intervene were take at 0 h,24 h,48 h after the models established.The neurological defects score was evaluated by Philips' criteria score in 1 d and 7 d. The physiological changes were observed by HE stained and electron microscope.Results The neurological defects score was singificiant lower in D group(41.50?8.18) than that in group A(82.20?8.08),B(63.60?6.22) and C (61.00?6.58)(allP
