Relationship between positron emission tomography and cognitive dsyfunction in patients with multiple sclerosis
- VernacularTitle:多发性硬化患者正电子发射体层成像显像与认知功能障碍的关系
- Author:
Liping CHEN
;
Weiping WU
;
Yanling MAO
- Publication Type:Journal Article
- Keywords:
multiple sclerosis;
cognitive function;
PET
- From:
Journal of Clinical Neurology
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between positron emission tomography (PET) and cognitive dsyfunction in patients with multiple sclerosis (MS). Methods 2 cases of MS were test with the Wechsler Intelligence Scale (WIS) or mini-mental state examination(MMSE), brain MRI and PET,then the results were analysed. Results The MMSE score of the case 1 was 19, which was lower than normal. The WIS score of the case 2 was normal. The PET of 2 patients showed that there were many hypo-metablism areas in cortex or subcortex.In addition,some cortical hypo-metablism areas of PET were not correspondingly found lesions in cortex or subcortex by MRI. Conclusions There are many hypo-metablism areas in cortex or subcortex in MS patients. The hypometablism areas may be correlated with the cognitive dysfunction of MS.
