PIWI and tumor
- VernacularTitle:PIWI和肿瘤
- Author:
Zihao CHENG
;
Yongping YOU
;
Zhen FU
- Publication Type:Journal Article
- Keywords:
PIWI;
Argonaute protein;
Tumor;
Gene therapy
- From:
Journal of Medical Postgraduates
2003;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
The PIWI family members are defined as conserved PAZ and PIWI domains and play important roles in stem-cell self-renewal,spermatogenesis,RNA interference and translational regulation.Recent researches have showen that some PIWI are specifically expressed in tumors and associated with tumor development and growth.PIWI is likely to be a new significante index for tumor diagnose and prognosis,the feasibility of PIWI acting in tumor gene theropy could be in vestigated by studying the mechanism of PIWI expression and regulation.
