Aminoglycoside Modifying Enzymes Genes of Multi-drug Resistant Acinetobacter baumannii:A Study of 20 Strains
- VernacularTitle:20株多药耐药鲍氏不动杆菌氨基糖苷类修饰酶基因研究
- Author:
Ailing FU
;
Yan XI
;
Xihua LI
;
Wanshan MA
;
Qilin GONG
;
Xiaohong SHI
;
Xiaojun SUN
- Publication Type:Journal Article
- Keywords:
Acinetobacter baumannii;
Resistant genes;
Aminoglycoside modifying enzymes
- From:
Chinese Journal of Nosocomiology
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the aminoglycoside modifying enzymes genes of multi-drug resistant Acinetobacter baumannii(MDR-ABA).METHODS The four kinds aminoglycoside modifying enzymes genes(aac(6′)-Ⅰad,aac(6′)-Ⅰb,aac(3)-Ⅰ,ant(3″)-Ⅰ) of 20 strains MDR-ABA were detected by PCR.RESULTS Among 20 MDR-ABA strains,12 strains of aac(3)-Ⅰ,15 strains of aac(6′)-Ⅰb,18 strains of ant(3″)-Ⅰwere positive,and aac(6′)-Ⅰad was negative.The new subtype aac(6′)-Ⅰad gene has not been found.CONCLUSIONS Twenty strains MDR-ABA aminoglycoside modifying enzymes genes are found in all the 20 MDR-ABA strains.The genotype is in accordance with antibiotics resistance.It can induce clone transmitting hospital infection.It is first time to study the aac(6′)-Ⅰad gene of A.baumannii in China.
