Drug Resistance of Extended Spectrum ?-Lactamases Producing Escherichia coli
- VernacularTitle:产超超广谱?-内酰胺酶大肠埃希菌的检测及耐药性分析
- Author:
Qiulian FAN
;
Zhenguo YAO
;
Huaguo GUO
;
Guoqiang CHEN
;
Hong WANG
- Publication Type:Journal Article
- Keywords:
Escherichia coli;
Super extended spectrum ?-lactamases;
AmpC lactamase;
Extended spectrum ?-lactamases
- From:
Chinese Journal of Nosocomiology
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the resistance phenotype and clinical feature of super extended spectrum ?-lactamases(SSBLs) producing Escherichia coli in order to provide reference for the clinical application of drugs.METHODS Totally 945 strains of ESBLs producing E.coli collected from Jan 2003 to Jun 2007 were identified by API microbiological assay system.Susceptbility tests were performed by K-B methods.Improved three-dimensional tests were adopted to test ESBLs and AmpC lactamase.Test data were analyzed statistically by WHONET 5.3 software.RESULTS From them eighteren strains of SSBLs producers were detected.Between the positive for ESBLs strains and the negative strains,there were some significant differences in the antimicrobial resistance(P