Fungus Infection after Heart Transplantation
- VernacularTitle:心脏移植术后真菌感染分析
- Author:
Yihong XIE
- Publication Type:Journal Article
- Keywords:
Heart transplantation;
Fungus;
Infection
- From:
Chinese Journal of Nosocomiology
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To explore the causes,distribution and treatment of fungus infection after heart transplantation.METHODS The fungus species,infectious sites,clinical manifestation,treatments and results of fungus infection among 15 patients after heart transplantation were investigated.RESULTS There were 6 fungus infection cases(40.0%) with 8 fungus species found from the oral secretion,sputum and urine.From them Candida albicans was in 6 cases(75.0%),Aspergrillus were in 1 case(12.5%)and other fungus was in 1 case(12.5%).The main manifestation included candidiasis,Aspergrillus pneumonia and mycotic cystitis.The treatment included local nystatin with glycerin liniment,rinsing bladder by diluted nystatin and iv amphotericin B and fluconazole.All fungus infection cases were cured in 7-21 days.CONCLUSIONS The risk factors of fungus infection after heart transplantation include hypoimmunity,dysbacteriosis,susceptibility and some staffs misplayed during sterile processes.The main pathogenic fungal species is C.albicans.Prevention,early detection and effective medication are very important to control the fungus infection after heart transplantation.
