Determination of free DNA level in plasma of patients with ovarian cancer
- VernacularTitle:卵巢恶性肿瘤患者血浆游离DNA含量测定及临床意义
- Author:
Ting GUAN
;
Changlan YE
;
Jie WU
;
Yuehua JIANG
- Publication Type:Journal Article
- Keywords:
ovarian neoplasms;
plasma;
free DNA
- From:
Journal of Jilin University(Medicine Edition)
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the plasma DNA level of patients with ovarian cancer and evaluate its potential clinical value.Methods Blood samples were collected from 30 ovarian cancer patients before and after surgery,and from 20 patients with ovarian benign tumor and 20 healthy women.The plasma DNA was extracted by commercial kit and detected by fluorescntmeter.Results The mean plasma DNA level in the cancer patients(25.33 ?g?L-1?17.69 ?g?L-1) was significantly higher than those in the benign tumor patients(10.28 ?g?L-1?4.80 ?g?L-1) and normal control(7.60 ?g?L-1?3.87 ?g?L-1)(P
