Inflammatory reactions following coronary stenting
- VernacularTitle:冠状动脉内支架置入后的炎症反应
- Author:
Yaguang HU
;
Huijiu ZHANG
;
Yingjie YANG
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2007;0(22):-
- CountryChina
- Language:Chinese
-
Abstract:
Coronary stent can cause mechanical injury to tunica intima and stimulation to vessel wall, resulting to platelet and inflammatory cell aggregation and infiltration, release of inflammation mediators, chemotatic factor, adhesion molecule and growth factor, and promoting migration and proliferation of vascular smooth muscle cells. The inflammatory reaction post stenting is highly correlated with intravascular restenosis. The drug-eluting stent against proliferation of vascular smooth muscle cells and inflammatory reaction can reduce the intensity and duration of body inflammatory reaction, improve stent technique, relieve damage of stenting to vessel wall, and reduce incidence of intravascular restenosis.
