Study on the activities of peroxisome ?-oxidation of peripheral blood mononuclear cell from T2DM patient
- VernacularTitle:2型糖尿病患者外周血单个核细胞过氧化物酶体脂肪酸?氧化活性变化的研究
- Author:
Jihong LI
;
Jilong LI
;
Zhidong YANG
- Publication Type:Journal Article
- Keywords:
Diabetes,type 2;
Peroxisome;
?-oxidation,fatty acid;
Fatty acyl-CoA oxidase
- From:
Chinese Journal of Diabetes
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the change of the activities of peroxisome ?-oxidation in T2DM patients with the lipid disorders.Methods We analyzed the changes of the activities of peroxisome ?-oxidation and fatty acyl-CoA oxidase and its mRNA expression in 112 cases of T2DM patients.Results We found that there was compensatory increase in activity of peroxisome ?-oxidation of T2DM patients.As compared with control group,the activity of fatty acyl-CoA oxidase of T2DM group was increased by 5%(P
