Research update on bleomycin-induced systemic sclerosis
- VernacularTitle:博来霉素诱导的硬皮病小鼠研究进展
- Author:
Kun XIAO
;
Xuan ZHANG
- Publication Type:Journal Article
- Keywords:
systemic sclerosis;
bleomycin;
animal model
- From:
Basic & Clinical Medicine
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Systemic Sclerosis(SSc) is a fibrotic disease characterized by immunological abnormalities,vascular injury and increased accumulation of extracellular matrix.The etiology has not been fully elucidated yet,so we need to establish a suitable animal model for research.This review is to introduce murine model of bleomycin-induced SSc,and summarize research works on the pathogenesis and treatment of SSc based on this model.
