Updated functions of the herpes simplex virus Us3 gene
- VernacularTitle:单纯疱疹病毒Us3基因功能的研究进展
- Author:
Jufeng ZHAO
;
Huilan YANG
;
Jianyong FAN
- Publication Type:Journal Article
- Keywords:
Herpes simplex virus;
Us3 gene;
Function
- From:
Journal of Medical Postgraduates
2003;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
The herpes simplex virus(HSV) Us3 gene encodes a ser/thr protein kinase(PK).As an accessory gene,it plays an important role in the regulation of the apoptosis of infected cells and virus release.Us3-induced alterations in the host cytomorphology are associated with enhanced intercellular virus spread,suggestive of a previously undescribed aspect of alphaherpesvirus spread.