Development and application of umbilical cord blood mesenchymal stem cells
- VernacularTitle:脐血间充质干细胞的研究发展与应用
- Author:
Xiaoping HUANG
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2007;0(21):-
- CountryChina
- Language:Chinese
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Abstract:
The paper aimed to review and update the studies on umbilical cord blood mesenchymal stem cells (UCMSCs) by retrieving Pubmed database and Chinese Journal Full-text Database. As a pluripotent stem cell, UCMSC exhibits abundant source, simple collection, preservation and transport with no allograft injection or ethical issues. UCMSCs can differentiate into cells of hematopoietic system and into osteoblast, chondrocyte, adipocyte, myocyte, neurocyte and hepatocyte under specific culture conditions. UCMSC surface antigen has no specificity. It has the features of mesenchymal cells, endothelial cells and epithelial cells. UCMSCs are widely used to treat many difficult diseases such as encephalomyelopathy, heart disease, diabetes mellitus, necrosis of the femoral head, and vascular occlusion of the lower limbs.
