Evaluation of bioavailability of ketoprofen 200 mg long acting tablets
- Author:
Nguyen Thi Kieu Anh
- Publication Type:Journal Article
- Keywords:
Drug
- MeSH:
Biological Availability;
Pharmaceutical Preparations;
Ketoprofen;
tablets;
drugs
- From:Pharmaceutical Journal
2003;326(6):22-24
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
In vitro bioavailability of ketoprofen 200mg long acting tablets by the oral were studied. Using basket dissolution tester at 120rpm. Released ketoprofen was determined by a UV – spectrophotometer at 260nm. Ketoprofen plasma levels on carefully chosen 6 healthy volunteers were within treatment which reached from 4 to 36 hours. 200mg ketoprofen LP tablets gradually released ketoprofen within 24 hours and released about 80% after 18 hours. Pharmacological parameter of ketoprofen 200mg long acting tablets have the same value compared with the results which have been published