?-Lactamases Gene of Multi-drug Resistant Acinetobacter baumannii:An Analysis of 20 Strains
- VernacularTitle:20株多药耐药鲍氏不动杆菌?-内酰胺酶基因研究
- Author:
Ailing FU
;
Yan XI
;
Xihua LI
- Publication Type:Journal Article
- Keywords:
Acinetobacter baumannii;
?-Lactamases;
Resistant genes
- From:
Chinese Journal of Nosocomiology
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the ?-lactamases gene of multi-drug resistant Acinetobactor baumannii(MDR-ABA).METHODS The blaTEM,blaSHV,blaPER,blaGES,blaIMP,blaVIM,blaSIM,blaOXA-23,blaADC and blaDHA genes of 20 MDR-ABA strains were detected by PCR.RESULTS Among 20 MDR-ABA strains,18 strains were with positive blaADC,11 strains were with positive blaTEM;the others were negative.Totally 19 strains were with genes correlated to ?-lactam antibiotics.The results indicated that the blaADC DNA sequence was a new subtype type compared with the blaADC sequence which had registered on America GenBank.CONCLUSIONS blaADC Gene and blaTEM gene have spread in the MDR-ABA group and a new blaADC subtype has been found.