Distribution and Drug Resistance Status of Extended-Spectrum ?-Lactamases Producing Klebsiella pneumoniae
- VernacularTitle:产超广谱?-内酰胺酶肺炎克雷伯菌感染分布及耐药性监测
- Author:
Dejun ZHAO
;
Weichan FU
;
Bixia ZHANG
;
Yujiang REN
;
Yan CAO
;
Yue MAO
;
Wei YANG
- Publication Type:Journal Article
- Keywords:
Klebsiella pneumoniae;
Extended-spectrum ?-lactamases;
Drug resistance status
- From:
Chinese Journal of Nosocomiology
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the distribution and drug resistance status of extended-spectrum ?-lactamases producing(ESBLs) Klebsiella pneumoniae and to provide the basis for clinic anti-infective treatment.METHODS To use ATB-expression analyzer to identify the microbe.The drug susceptibility was tested with the K-B method and the ESBLs producing strains detected by diffusion confirmed test.RESULTS Among 137 strains of identified K.pneumoniae,34.3% of them(47 strains)produced ESBLs,and most had been shown in geriatrics ward.The drug resistance rate of ESBLs producing K.pneumoniae was higher than that in non-producing ESBLs one.So imipenem should be considered to be a preferred antibiotic when used on K.pneumoniae seriously infected cases.CONCLUSIONS The drug resistance of K.pneumoniae is a serious problem,we should pay attention on the status of ESBLs distribution,based on the susceptibility to choose the reasonable antibacterial to avoid the producing ESBLs bacteria spread out.
