Expression of TNF-? and IgE in Peripheral Blood of Children Patients with Mycoplasma pneumoniae Infection and Bronchial Asthma
- VernacularTitle:哮喘合并支原体感染患儿血清TNF-?与IgE水平的表达
- Author:
Zongliang YAO
;
Lanyin LI
;
Aihua WAN
- Publication Type:Journal Article
- Keywords:
Respiratory tract;
Mycoplasma pneumoniae;
Asthma;
TNF-?;
IgE
- From:
Chinese Journal of Nosocomiology
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To study the expression of the level of tumor necrosis factor alpha(TNF-?) and total IgE in Mycoplasma pneumoniae(MP) infection and bronchial asthma,and to analyze its relation with disease severity.METHODS The enzyme-linked immunosorbent assay(ELISA) was adopted to measure the level TNF-? and radioimmunoassay(RIA) to measure IgE in 42 children patients with asthma and MP infection as a test group,and 36 healthy children as a control group.RESULTS Among patients with asthma and MP infection TNF-? [(37.96?9.76)?g/L] and IgE [(310.57?30.39) mg/ml] had a significantly higher level than control group [(16.39?6.87)?g/L and (201.50?16.98)mg/ml],the statistical differences were significant(t=11.23;t=19.56 P
