Research progress on the DNA vaccine of HSP70 fused with tumor antigen gene
- VernacularTitle:热休克蛋白70融合肿瘤抗原基因的DNA疫苗研究进展
- Author:
Jinbao ZONG
;
Xuemei XU
- Publication Type:Journal Article
- Keywords:
heat shock protein 70;
DNA vaccine
- From:
Basic & Clinical Medicine
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
A variety of heat shock protein 70(HSP70)-associated therapeutic vaccines including protein vaccine,peptide vaccine,tumor cell vaccine and DNA vaccine,have been developed and applied in anti-tumor immunotherapy,in which HSP70-fused DNA vaccine attracts our attention with its superiority.It not only induces consistent anti-tumor immune response but also helps sustain immune memory.In this article we reviewed the function and application of HSP70 in the therapeutic tumor DNA vaccine.
