The roles of astrocytes in the pathogenesis of Parkinson's disease
- VernacularTitle:星形胶质细胞在帕金森病发病机制中的作用
- Author:
Fengyue LU
;
Yongmei ZHAO
- Publication Type:Journal Article
- Keywords:
Parkinson's disease;
astrocyte;
neuroprotection
- From:
Basic & Clinical Medicine
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Parkinson's disease(PD) is a progressive neurodegenerative disorder harming mainly the elderly.Astrocyte may be involved in the pathogenesis of PD.However,it also plays a protective role in PD by releasing neurotrophic factors and glutathione to support the survival of dopaminergic neurons.Astrocyte may also release proinflammatory cytokines to promote the development of PD.
