The sensitive of antibiotics of Pseudomonas aeruginosa strain isolated in some hospitals in Hanoi city
- Author:
Le Thi Anh Hong
- Publication Type:Journal Article
- Keywords:
antibiotic, Pseudomonas aeruginosa , hospital
- MeSH:
Anti-Bacterial Agents;
Pseudomonas aeruginosa;
Drug Resistance, Microbial
- From:Journal of Vietnamese Medicine
2004;303(10):1-6
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Pseudomonas aeruginosa is resistant many antibiotics currently, including new generation, broad spectrum antibiotics that were very effective with other bacteria. Thus, it's difficult to treat P. aeruginosa infection with these antibiotics. Author collected P. aeruginosa strains from some hospitals in Hanoi, tested with more antibiotics in order to determine antibiotic resistant rate and types, to orient some mechanisms of antibiotic resistance of P. aeruginosa. Materials is 97 strains of P. aeruginosa isolated from blood and pus of patients treated at Bach Mai Hospital and National Institute of Burn from August 2002 to November 2003. Method: disk diffusion antibiotic sensitivity testing (Kirby - Bauer test). Results: Isolated P. aeruginosa strains are multiple antibiotic resistant (8 of 16 antibiotics), especially hospital infection strains are resistant 100% of tested antibiotics. It showed the potential roles of some enzymes such as penicillinase, cephalosporinase, AAC(6), ANT(2")-1, and ANT(2") enzymes that inhibit effects of antibiotics in bacterium cell
