Human Serum Trypanosome Lytic Factor and Serum Resistance-Associated Protein of Trypanosome
- VernacularTitle:人血清锥虫溶解因子与锥虫抗血清相关蛋白
- Author:
Zhi LI
;
Zhaorong LUN
- Publication Type:Journal Article
- Keywords:
Trypanozoon;
Trypanosome lytic factor (TLF);
Serum resistance-associated protein
- From:
Chinese Journal of Parasitology and Parasitic Diseases
1987;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Human African trypanosomiasis is caused by the infection of Trypanosoma brucei gambiense or T.b. rhodesiense, while another morphologically identical subspecies, T.b.brucei, and other closely related species, T.equiper-dum and T.evansi, are considered not infectious to human. This is highly related to the trypanosome lytic factor (TLF) found in normal human serum (NHS) and the serum resistance-associated (SRA) protein of trypanosomes infectious to human. We reviewed the research progress in TLF and its role in trypanosome lysis as well as the mechanism of SRA against the TLF.
