Prospective Analysis on Strategy of OPV Switching to Sabin-IPV at the Endgame of Poliomyelitis Eradication in China
- VernacularTitle:中国在消灭脊髓灰质炎(脊灰)后期使用赛宾株-脊灰灭活疫苗替代口服脊灰减毒活疫苗策略的前瞻性分析
- Author:
Aiqiang XU
;
Renpeng LI
;
Li LI
- Publication Type:Journal Article
- Keywords:
Poliomyelitis;
OPV;
Sabin-IPV;
Immunization strategy
- From:
Chinese Journal of Vaccines and Immunization
2008;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the immunization strategy at the endgame of poliomyelitis eradication in China.Methods To search the related study databases by the mean of evidence based medicine,and to investigate the update status of production and usage of polio vaccine in China.The general prospective analysis was conducted on aspects of the comparison of different immunization strategies,the feasibility of oral poliovirus vaccine(OPV)switching to Sabin strain inactivated poliovirus vaccine(Sabin-IPV)and the Sabin-IPV immunization schedule.Results The immunization strategy of OPV switching to IPV should be considered to choose in China because the domestic Sabin-IPV products will be registered soon and the switching feasibility is already provided with the conditions of police,technique,vaccine supply,and other guarantee.The routine immunization of Sabin-IPV can be carried out referring to the update OPV immunization schedule.Conclusion The study on immunization strategy at the endgame of poliomyelitis eradication should be further enhanced and the preparation of OPV switching Sabin-IPV should be considered in China.
