The variance of PKC in cardiac cells of SMDS victims
- VernacularTitle:PKC在青壮年猝死综合征心肌组织中的变化
- Author:
Hongquan XU
;
Hualan JING
;
Yijun ZHANG
;
Jiquan YAN
;
Yongxi WEN
;
Hong LIN
;
Fuxue JIANG
- Publication Type:Journal Article
- Keywords:
forensic pathology;
PKC;
cardiogenic;
sudden death;
immunohistochemical staining
- From:
Chinese Journal of Forensic Medicine
2009;24(6):396-397,后插1
- CountryChina
- Language:Chinese
-
Abstract:
Objective This article aims to explore the relationship between PKC and SMDS(sudden manhood death syndrome,SMDS).Methods By way of immunohistochemical staining of left,right ventricular tousles,sino atrial node and atrioventricular node from 30 cases of SMDS group and 20 cases of control group,we observed and measured the expression and the intensity variance of PKC in myocardial ceHs with graphical analysis software.Results The average gray value and total area of PKC in myocardial cells of cases in the SMS group are obviously higher than that of cases in control group(P<0.05).And in the SMDS group,the average gray value of PKC in sino atrial node is higher than that in atrioventricular node.Conclusion As one way of humoral regulation,PKC is involved in the process of protecting the heart from impairment in SMDS.and it can be considerated as a reference index to identify the SMDS.
